Study on Anthelmintic and Antidiabetic activity of leaves of AcanthospermumhispidumDC

AcanthospermumhispidumDC.is found in the tribal area of Koraput and Malkangiri districts andtraditionally used by the tribal people as anthelmintic, antidiabetic, antihypertensive, carminative and antifungal. No systematic study was conducted on A .hispidumDC. The present work was conducted to investigate the anthelmenticand Antidiabetic activities on the leaves of A.hispidumDC.Petrolium ether, Chloroform and Hydroalcoholic (70 % V/V) extracts were prepared and subjected to above mentioned studies. Anthelmentic activity was tested on adult Indian earthworms, Pheretimapostuma, Glibenclamideand Albendazolewas selected as standard for Antidiabetic and Anthelmintic activity respectively. Result showed the hydroalcoholic extract showed significant activity on both cases as compared to standard. The data were verified as statistically significant by using one way ANOVA at 5 % level of significance (p < 0.05).